To prepare a texas smoked barbecue meatloaf recipe, first you need to prepare the ingredients. First, you'll need the following ingredients: 1 pound brisket, 2 tablespoons barbecue sauce, 1 tablespoon ketchup, 1/2 teaspoon paprika, 1/4 teaspoon cayenne pepper, salt, and pepper to taste. Place all of the above ingredients in the large bowl and mix well. Then, pour the meat mixture into the bowl. Cover with plastic wrap and refrigerate for at least 2 hours. Preheat the oven to 375 degrees F (190 degrees C).